Built in 1907, the Fairmont San Francisco is a grand hotel with impeccable service. Located atop Nob Hill, with impressive views, the hotel has been restored to its former glory. The 591 plush guest rooms are decorated in an early 1900s style, but with modern amenities like marble baths, flat screen TVs, Frette linens, and MP3 docking stations. Your first time to San Francisco? The concierge knows all the best shops and attractions, plus out-of-the-way stuff only locals know about. If you want to hang out at one of America's best bars, head for The Tonga Room. A Bay area fixture since 1945, it's an all-out indoor Tiki bar with thatch-roof huts and central lagoon, updated with a sleek granite bar, snow leopard bar stools, and red leather banquettes. Just want a good cup of coffee? Relax at Caffé Centro, a European-style coffee house. Next day, hit the gym early. The Fairmont offers a complete spa and health club, including daily aerobics, pilates, yoga, and spinning classes.